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Welcome to miRNA-eQTL

miRNA-eQTL aims to comprehensively provide miRNA related cis-eQTLs (SNPs affect local miRNA gene expression) and trans-eQTLs (SNPs affect distant miRNA gene expression) in different cancer types of The Cancer Genome Atlas (TCGA). We have identified 87,833 and 5,170 eQTL−gene pairs at FDR < 0.05 in 33 cancer types in cis-eQTL and trans-eQTL analysis, respectively. To prioritize promising miRNA-eQTLs, we identified miRNA-eQTLs associated with patient survival times (survival-eQTLs) and located in GWAS linkage disequilibrium (LD) regions (GWAS-eQTLs). In survival-eQTL, we identified 116 eQTLs associated with patient overall survival times, and in GWAS-eQTL, we identified 26,908 eQTLs pairs that overlap with GWAS linkage disequilibrium (LD) regions.

Users can do:

          Browse or search miRNA-eQTLs across different cancer types
          Browse or search miRNA-eQTLs associated with patient overall survival times across different cancer types
          Browse or search miRNA-eQTLs in GWAS linkage disequilibrium (LD) regions
          Download figures and all miRNA-eQTLs results

e.g. SNP "rs10132271", Gene symbol "hsa-miR-3130-5p"



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