Welcome to miRNA-eQTL
miRNA-eQTL aims to comprehensively provide miRNA related cis-eQTLs
(SNPs affect local miRNA gene expression)
and trans-eQTLs (SNPs affect distant miRNA gene expression) in different cancer types of The Cancer Genome Atlas
(TCGA). We have identified 87,833 and
5,170 eQTL−gene pairs at FDR < 0.05 in 33 cancer types in cis-eQTL and
trans-eQTL analysis, respectively. To prioritize promising miRNA-eQTLs, we identified miRNA-eQTLs
associated with
patient survival times (survival-eQTLs) and located in GWAS linkage disequilibrium (LD) regions (GWAS-eQTLs). In
survival-eQTL, we identified 116 eQTLs
associated with patient overall survival times, and in GWAS-eQTL, we
identified 26,908 eQTLs pairs that overlap with GWAS linkage disequilibrium (LD) regions.
Users can do:
e.g. SNP "rs10132271", Gene symbol "hsa-miR-3130-5p"