Target AC |
Target name
|
Species |
Gene |
EC |
PDB template |
Inhibitor |
Identity |
Modeled Structure |
|
16S rRNA-processing protein |
Eca |
rimM |
- |
No |
39% |
  |
|||
1-deoxy-D-xylulose 5-phosphate reductoisomerase |
Eca |
dxr |
1.1.1.267 |
Fosmidomycin |
74% |
 |
|||
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase |
Eca |
folK |
2.7.6.3 |
Adenosine-5'-diphosphate |
67% |
 |
|||
3,4-dihydroxy-2-butanone-4-phosphate synthase |
Eca |
ribA, |
4.1.99.12 |
No |
82% |
 |
|||
3-dehydroquinate synthase |
Eca |
aroB |
4.2.3.4 |
No |
34% |
 |
|||
3-deoxy-manno-octulosonate cytidylyltransferase |
Eca |
kdsB |
2.7.7.38 |
No |
76% |
 |
|||
3-phosphoshikimate 1-carboxyvinyltransferase |
Eca |
aroA |
2.5.1.19 |
Shikimate-3-phosphate |
82% |
 |
|||
Acetyl-CoA carboxylase subunit beta |
Eca |
accD |
6.4.1.2 |
No |
88% |
 |
|||
Alanine racemase |
Eca |
alr, dadX |
5.1.1.1 |
No |
72% |
 |
|||
Alkylhydroperoxidase AhpD |
Psp |
- |
- |
(4S)-2-methyl-2,4-pentanediol |
36% |
 |
|||
Arginine deiminase |
Pss |
- |
3.5.3.6 |
No |
81% |
 |
|||
Aspartate carbamoyltransferase catalytic subunit |
Eca |
pyrB |
2.1.3.2 |
N-phosphonacetyl-L-aspartic acid |
85% |
 |
|||
Aspartate-semialdehyde dehydrogenase |
Eca |
asd |
1.2.1.11 |
S-methyl-L-cysteine sulfoxide |
86% |
 |
|||
Betaine aldehyde dehydrogenase |
Eca |
betB |
1.2.1.8 |
No |
49% |
 |
|||
Beta-ketoacyl-[ACP] synthase I |
Xac |
fabB |
- |
No |
63% |
 |
|||
Cell division protein FtsZ |
Eca |
ftsZ |
- |
Guanosine 5'- diphosphate |
57% |
 |
|||
Chorismate synthase |
Eca |
aroC |
4.2.3.5 |
No |
44% |
 |
|||
Cystathionine gamma-synthase |
Eca |
metB |
4.2.99.9 |
2,4-dioxo-pentanedioic acid |
86% |
 |
|||
Cytidylate kinase |
Eca |
cmk |
2.7.4.14 |
Cytidine 5-diphosphate |
83% |
 |
|||
D-alanine--D-alanine ligase |
Eca |
ddl |
6.3.2.4 |
2-[(1 -amino-ethyl)-phosphate-phosphinoyloxy]-butyricAcid |
70% |
 |
|||
D-alanyl-D-alanine carboxypeptidase |
Eca |
dacB, pbpE |
3.4.16.4 |
N1-[(1R)-1-(dihydroxyboryl)ethyl]-N2-[(tert-butoxycarbonyl)-D-gamma-glutamyl]-N6-[(benzyloxy)carbonyl-L-lysinamide |
81% |
 |
|||
Dihydrofolate reductase |
Eca |
folA |
1.5.1.3 |
Methotrexate |
79% |
 |
|||
Dihydroneopterin aldolase |
Eca |
folB |
4.1.2.25 |
Neopterin |
77% |
 |
|||
Dihydropteroate synthetase |
Eca |
folP |
2.5.1.15 |
No |
73% |
 |
|||
DNA topoisomerase III |
Eca |
topA, topB |
5.99.1.2 |
No |
82% |
 |
|||
Elongation factor G |
Eca |
fusA |
- |
No |
89% |
 |
|||
Fumarate reductase flavoprotein subunit |
Eca |
frdA |
1.3.1.6 |
2-heptyl-4-hydroxy quinoline n-oxide |
85% |
 |
|||
Isocitrate lyase |
Eca |
aceA |
4.1.3.1 |
Pyruvic acid |
86% |
 |
|||
Isoleucyl-tRNA synthetase |
Eca |
ileS |
6.1.1.5 |
Pseudomonic acid |
41% |
 |
|||
Malonyl-CoA:acyl carrier protein transacylase |
At58 |
fabD |
- |
No |
47% |
 |
|||
Nicotinate-nucleotide pyrophosphorylase |
Rs1000 |
nadC |
2.4.2.19 |
Quinolinic acid |
52% |
 |
|||
Pantothenate kinase |
Eca |
baf, panK, coaA, tdk |
2.7.1.33 |
No |
84% |
 |
|||
Phosphomannomutase /phosphoglucomutase |
Xf9a5c |
manB, xanA, algC |
5.4.2.8 / 5.4.2.2 |
L(+)-Tartaric acid |
32% |
 |
|||
Polyphosphate kinase |
Eca |
ppk |
2.7.4.1 |
No |
83% |
 |
|||
Protease II |
Eca |
ptrB |
3.4.21.83 |
N-[(Benzyloxy)Carbonyl]-L-Alanyl-L-Proline |
27% |
 |
|||
Pyridoxal phosphate biosynthetic protein pdxJ |
Eca |
pdxJ |
- |
1-Deoxy-D-xylulose 5-phosphate |
80% |
 |
|||
Riboflavin synthase subunit alpha |
Eca |
ribC, ribE |
2.5.1.9 |
No |
76% |
 |
|||
Riboflavin synthase subunit beta |
Eca |
ribH |
2.5.1.9 |
No |
76% |
|
|||
Signal peptidase I |
Eca |
lepB |
3.4.21.89 |
Arylomycin A2 |
74% |
 |
|||
Thioredoxin reductase |
Eca |
trxB |
1.6.4.5 |
Flavin-adenine dinucleotide |
87% |
 |
|||
Topoisomerase IV subunit A |
Eca |
parC |
5.99.1.- |
No |
82% |
 |
|||
Topoisomerase IV subunit B |
Eca |
parE |
5.99.1.- |
No |
82% |
|
|||
UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase |
Eca |
lpxC |
- |
(2R)-N-hydroxy-3-naphthalen-2-yl-2-[(naphthalen- 2-ylsulfonyl)amino] propanamide |
58% |
 |
|||
Undecaprenyl pyrophosphate synthetase |
Eca |
uppS |
2.5.1.31 |
Farnesyl diphosphate |
77% |
 |
|||
Beta-lactamase |
Xac |
- |
3.5.2.6 |
10-((2r)-2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane 1,4,7-triacetic acid |
28% |
|
|||
Cytochrome P450 hydroxylase |
Eca |
- |
- |
No |
25% |
- |
|||
Dihydroorotate dehydrogenase 2 |
- |
pyrD |
1.3.3.1 |
- |
- |
- |
- |
||
DNA gyrase subunit A |
Eca |
gyrA |
5.99.1.3 |
- |
- |
- |
- |
||
DNA gyrase subunit B |
Eca |
gyrB |
5.99.1.3 |
- |
- |
- |
- |
||
Glutathionylspermidine synthase |
Eca |
- |
6.3.1.8 |
- |
- |
- |
- |
||
Immunogenic protein |
At58 |
pp26 |
- |
- |
- |
- |
- |
||
|
Eca |
guaB |
1.1.1.205 |
- |
- |
- |
- |
||
Penicillin binding protein |
At58 |
- |
3.4.16.4 |
- |
- |
- |
- |
||
Sortase |
Cmm |
- |
3.4.22.B21 |
- |
- |
- |
- |